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). It got me thinking - for months preceding my H's affair, he had been suffering a lot from allergies, much worse than he ever had before. I have read evidence of a connection between allergies and autism and possibly ADHD, but is there a connection between allergies and depression, apart from the fact that allergies can make you pretty miserable? If they can cause changes in brain chemistry which lead to autistic behavior, do they also cause changes which lead to depression?